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Hybridtide™ Platform

Longevity Biotech is developing a new class of therapeutic candidates called Hybridtides™. The unique Hybridtide™ scaffold provides critical enhancements over traditional peptide development efforts (e.g. PEG, Lactam Bridges, aka ‘Staples’) as well as macrocycles, D-peptides and peptoids.

By leveraging non-natural amino acids, Longevity Biotech has unprecedented control over both molecular conformation and structure-based design elements. Hybridtides™ offer a unique peptidomimetic scaffold that both metabolically stable and structural stable.  In addition to improving the stability of these peptides, product profile advantages include robust target selectivity, low immunogenicity, and the potential for signal bias.

We work with partners to incorporate the Hybridtide™ Platform to improve their product profiles.  If you are interested in partnering with Longevity Biotech, please contact us to learn more.

The Hybridtide™ platform allows for highly tunable and distinct properties and therefore delivers compelling product profiles.  

An example of this is the tunable affinity for the GLP-1 vs. GIP receptors.   A small library of peptides is able to deliver remarkable results. 

Contact us to learn how Hybridtides™ can help your peptide program today!